WDKA began broadcasting on June 5, 1997. It was a UPN affiliate broadcasting an analog signal on UHF channel 49. In 2000, WDKA switched affiliations with low-powered station WQTV-LP (licensed to Murray, Kentucky) and repeater WQWQ-LP to become an affiliate of The WB. The station became a MyNetworkTV affiliate on September 5, 2006. In the same month, The WB and UPN merged to become The CW, and WQTV-LP was announced to become The CW affiliate for Paducah.
GetTV, a new movie-oriented network owned by Sony Pictures Television, started broadcasting over WDKA-DT2 in July 2014 (exact date unknown) as part of a deal with Sinclair Broadcasting to add 33 markets to GetTV's roster of affiliates.
On August 30, 2014, WDKA became a charter affiliate of Sinclair's ad-hoc syndicated television network, the American Sports Network. ASN provides Ohio Valley Conference basketball and Conference USA football and basketball games to the station's viewers. The ASN's programming content replaces Southeastern Conference football and basketball broadcasts from ESPN Plus-oriented SEC TV, which was run from 2009 until 2014, which was discontinued because of the launch of the cable-exclusive SEC Network.
On March 3, 2016, WDKA Acquisition Corporation (owned by Paul T. Lucci,) filed to sell WDKA to Sinclair's subsidiary WDKA Licensee, LLC. Sinclair bought the station for $1.9 million. The sale was completed on September 1, 2017.