He was beatified by Pope Paul V on 25 October 1619 and canonized by Pope Gregory XV on 12 March 1622. In 1624 he was made co-patron of Navarre alongside Santiago. Known as the "Apostle of the Indies," and the "Apostle of Japan", he is considered to be one of the greatest missionaries since Saint Paul. In 1927, Pope Pius XI published the decree "Apostolicorum in Missionibus" naming Saint Francis Xavier, along with Saint Thérèse of Lisieux, co-patron of all foreign missions. He is now co-patron saint of Navarre with San Fermin. The Day of Navarre (Día de Navarra) in Spain marks the anniversary of Saint Francis Xavier's death, on 3 December 1552.
Francis Xavier was born in the royal castle of Xavier, in the Kingdom of Navarre, on 7 April 1506 according to a family register. He was the youngest son of Juan de Jasso y Atondo, seneschal of Xavier castle, who belonged to a prosperous farming family and had acquired a doctorate in law at the University of Bologna, and later became privy counsellor and finance minister to King John III of Navarre (Jean d'Albret). Francis's mother was Doña María de Azpilcueta y Aznárez, sole heiress of two noble Navarrese families. He was thus related to the great theologian and philosopher Martín de Azpilcueta.
In 1512, Ferdinand, King of Aragon and regent of Castile, invaded Navarre, initiating a war that lasted over 18 years. Three years later, Francis's father died when Francis was only nine years old. In 1516, Francis's brothers participated in a failed Navarrese-French attempt to expel the Spanish invaders from the kingdom. The Spanish Governor, Cardinal Cisneros, confiscated the family lands, demolished the outer wall, the gates, and two towers of the family castle, and filled in the moat. In addition, the height of the keep was reduced by half. Only the family residence inside the castle was left. In 1522 one of Francis's brothers participated with 200 Navarrese nobles in dogged but failed resistance against the Castilian Count of Miranda in Amaiur, Baztan, the last Navarrese territorial position south of the Pyrenees.
In 1525, Francis went to study in Paris at the Collège Sainte-Barbe, University of Paris, where he would spend the next eleven years. In the early days he acquired some reputation as an athlete and a high-jumper.
In 1529, Francis shared lodgings with his friend Pierre Favre. A new student, Ignatius of Loyola, came to room with them. At 38, Ignatius was much older than Pierre and Francis, who were both 23 at the time. Ignatius convinced Pierre to become a priest, but was unable convince Francis, who had aspirations of worldly advancement. At first Francis regarded the new lodger as a joke and was sarcastic about his efforts to convert students. When Pierre left their lodgings to visit his family and Ignatius was alone with Francis, he was able to slowly break down Francis's resistance. According to most biographies Ignatius is said to have posed the question: "What will it profit a man to gain the whole world, and lose his own soul?" However, according to James Broderick such method is not characteristic of Ignatius and there is no evidence that he employed it at all.