After the collapse of the Kingdom of Urartu (Ararat), the region was placed under the administration of the Median Empire and the Scythians. Later the territory was conquered by the Achaemenid Empire, which incorporated it as a satrapy, and thus named it the land of "Armina" (in Old Persian; "Harminuya" in Elamite; "Urashtu" in Babylonian).
The Orontid Dynasty, or known by their native name, Eruandid or Yervanduni, was a hereditary dynasty of ancient Armenia, and the rulers of the successor state to the Iron Age kingdom of Urartu (Ararat). Historians state that the dynasty was of Iranian origin, and suggest, albeit not clearly, that it held dynastic familial linkages to the ruling Achaemenid dynasty. Throughout their existence, the Orontids stressed their lineage from the Achaemenids in order to strengthen their political legitimacy.
Members of the dynasty ruled Armenia intermittently during the period spanning from the 6th to at least the 2nd centuries BC, first as client kings or satraps of the Median and Achaemenid empires and later, after the collapse of the Achaemenid empire, as rulers of an independent kingdom, and later as kings of Sophene and Commagene, which eventually succumbed to the Roman Empire.
The Orontids established their supremacy over Armenia around the time of the Scythian and Median invasion in the 6th century BC. Its founder was Orontes I Sakavakyats (Armenian: Երվանդ Ա Սակավակյաց, Yervand I Sakavakyats). His son, Tigranes Orontid, united his forces with Cyrus the Great and killed Media's king. Moses of Chorene called him "the wisest, most powerful and bravest of Armenian kings."
From 553 BC to 521 BC, Armenia was a subject kingdom of the Achaemenid Empire, but when Darius I was king, he decided to conquer Armenia. He sent an Armenian named Dâdarši to stop a revolt against Persian rule, later replacing him with the Persian general, Vaumisa, who defeated the Armenians in 521 BC. Around the same time, another Armenian by the name of Arakha, son of Haldita, claimed to be the son of the last king of Babylon, Nabonidus, and renamed himself Nebuchadnezzar IV. His rebellion was short lived and was suppressed by Intaphrenes, Darius' bow carrier.
After the Battle of Gaugamela (331 BC), Orontes III was able to regain independence for Armenia. But in 201 BC, Armenia was conquered by Artashes, a general from the Seleucid Empire, and also said to be a member of Orontid dynasty. The last Orontid king Orontes IV was killed, but the Orontids continued to rule in Sophene and Commagene until the 1st century BC.
In two inscriptions of king Antiochus I of Commagene on his monument at Mount Nemrut, Orontes I (son of Artasouras and husband of Artaxerxes' daughter Rhodogoune), is reckoned as an ancestor of the Orontids ruling over Commagene, who traced back their family to Darius the Great.