The road received much use before and after the Battle of Sekigahara in 1600. Fukushima Masanori, the leader of the eastern armies, traveled the Minoji from Okoshi (modern-day Ichinomiya) to Mino Province for the battle. Tokugawa Ieyasu, the victor of the battle, traveled the route afterwards to a hero's welcome. It was also referred to as the Kichirei Kaidō (吉例街道).
Including the starting and ending points, there were only nine post stations on the Minoji. The route was named after Mino Province, which makes up the southern portion of the modern-day Gifu Prefecture. As such, the route spans both Aichi and Gifu prefectures. The stations are listed below, with their current municipality in parentheses.
The Tōkaidō Main Line, the Tōkaidō Shinkansen and the Tōmei and Meishin expressways all follow the historical Tōkaidō from Tokyo to Nagoya. From Gifu to Kusatsu, the routes all follow the historical Nakasendō. As such, the route between Nagoya and Gifu is also called "Minoji." Also, the modern Route 22 follows the path of the Minoji.