Provincial Trunk Highway 1 (PTH 1) is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan (to the west) and Ontario (to the east). The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
PTH 1 is a very important part of the national highway system. It is the only road that links the province of Manitoba with the province of Ontario, making it a major section of Canada's primary commercial and leisure route for all traffic travelling between Canada's largest cities, from Toronto and Montreal in the east to Calgary and Vancouver in the west.
The highway is routed from west to east across the province of Manitoba. It begins at the western provincial boundary with Saskatchewan, connecting with Saskatchewan's Highway 1 to become Manitoba Trans-Canada 1. The highway is designated as T-C 1 throughout Manitoba until it reaches the eastern provincial boundary with Ontario, where it continues as the main route to Kenora, Ontario and the rest of Eastern Canada as Highway 17.
The entire length of the Trans-Canada Highway in the province of Manitoba is a 4-lane divided highway, with the exception of the Winnipeg city route and an 18 kilometre section in eastern Manitoba between the town of Falcon Lake and the Manitoba-Ontario provincial boundary which is a two-lane highway.