Sangaré, who was born in Bamako, was a founding member of the Party for Democracy and Progress (PDP), which was created in 1991. He served as its Secretary-General and then as its Vice-President. He left the PDP and was a founding member of the CDS in 1996; he has been President of the CDS since then. Sangaré ran as the CDS candidate in the April 2002 presidential election, finishing in eighth place with 2.21% of the vote.
On March 27, 2007, he was again designated as the CDS candidate for the April 2007 presidential election, and in the election he placed fifth with 1.58% of the vote. In the 2007 election, he was one of four candidates participating in the Front for Democracy and the Republic opposition coalition.