The first series aired between 21 February and 14 March 2009 and was won by Robert Webb. It raised over £300,000 for Comic Relief. The second series, in aid of Sport Relief, aired from 20 February 2010 until 14 March and was won by Rufus Hound. The third series aired between 19 February 2011 and 12 March in aid of Comic Relief, and was won by James Thornton and Charlie Baker. A fourth series aired from 18 February until 17 March 2012 in aid of Sport Relief, and was won by Rowland Rivron. The fifth ran from 16 February 2013 until 9 March 2013, and was won by Antony Cotton. The series' finale was the last Saturday night show to be broadcast live from BBC Television Centre.
On 6 October 2016, the BBC announced that the show would return for Red Nose Day 2017 as Let's Sing and Dance for Comic Relief. On 28 October 2016, it was announced that Mel Giedroyc and Sue Perkins would host the show.
The four-part series was announced by the BBC in January 2009 as part of the corporation's events surrounding Red Nose Day 2009, hosted by Steve Jones and Claudia Winkleman. For the first three programmes, six celebrity acts each recreated a famous dance routine. Viewers then voted for their favourite performer, with the proceeds from their calls going to Comic Relief/Sport Relief. The act with the most viewer votes went through to the final, and the three panellists chose a second act from the top three to go through. The top six acts then returned for the final.
The guest panellists the first week were Emma Bunton and Michael McIntyre. The programme also premièred the video for the charity single "Islands in the Stream" released by Gavin & Stacey actors Ruth Jones and Rob Brydon and featuring Tom Jones. The acts were, in order of performance: