A cell junction
(or intercellular bridge
) is a type of structure that exists within the tissue
of some multicellular organisms
, such as animals
. Cell junctions consist of multiprotein complexes
that provide contact between neighboring cells
or between a cell and the extracellular matrix
. They also build up the paracellular barrier of epithelia and control the paracellular transport
. Cell junctions are especially abundant in epithelial
Cell junctions are especially important in enabling communication between neighboring cells via specialized proteins called communicating junctions. Cell junctions are also important in reducing stress placed upon cells.
Combined with CAMs and ECM, cell junctions help hold animal cells together.
In vertebrates, there are three major types of cell junction:
Invertebrates have several other types of specific junctions, for example septate junctions or the C. elegans apical junction.
This page was last edited on 20 June 2018, at 03:48 (UTC)
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