Jota finished his development with Galician club Celta de Vigo, after joining the club's youth system at the age of 13. He made his first-team debut on 29 January 2011, coming on as an 89th-minute substitute for Enrique de Lucas in a 1–1 draw with Barcelona B in the Segunda División. Jota played twice in April 2011, making his first start in a 1–0 win away to Albacete on 17 April – he lasted 73 minutes before being replaced by Mateo – and finished the 2010–11 season with four appearances. His only first-team appearance of the 2011–12 season came as a 73rd-minute substitute for Joan Tomàs in a 3–1 Copa del Rey third round win over Real Valladolid on 12 October 2011. He did however captain and top-score for Celta's B-team as they finished bottom of the 2011–12 Segunda División B. With Celta's first team back in La Liga for the 2012–13 season, Jota was not in the manager's plans, and he spent the next season out on loan.
Although he said he only wanted to leave on a permanent transfer, Jota was loaned to Real Madrid Castilla, newly promoted to the Segunda División for the 2012–13 season. The deal included an option to purchase for a fee of around €1 million. Mostly confined to the bench, he made just three appearances.
On Jota's return to Celta, he found new manager Luis Enrique equally willing to dispense with his services, so he again went out on loan, joining Eibar for the 2013–14 Segunda División season. He instantly broke into the team and made 37 appearances during the season. On 25 May 2014, Jota scored the only goal of the game at home to Deportivo Alavés that confirmed Eibar's promotion to La Liga for the first time in the club's history. Jota finished the season with 11 goals and collected a Segunda División winners' medal after Eibar were promoted as champions. In recognition of his performances, Jota was one of three nominees for the Best Attacking Midfielder award at the 2014 LFP Awards – he lost out to Ayoze Pérez – and was named in the division's Team of the Year.
Eduardo Berizzo – Luis Enrique's successor – saw Jota as part of his vision for Celta. The club opened talks with Jota's father, who acted as his representative, over a contract extension, but no agreement could be reached. Injury kept the player out of pre-season, and his omission from the team at the beginning of the season was attributed to concerns he might suffer a relapse, and had no connection to his contractual situation. Jota left Celta in August 2014, having made just five senior appearances.
On 15 August 2014, Jota signed a three-year deal with English club Brentford, newly promoted to the Championship, for an undisclosed fee, reported in Spain as €1.5 million. He made his debut as a 64th-minute substitute for Moses Odubajo in a 2–1 victory over Blackpool at Bloomfield Road four days later. He made his first start for the Bees in the following game, against Birmingham City, but lasted only 17 minutes before being sacrificed for Harlee Dean after Tony Craig received a straight red card. On his seventh appearance, Jota scored his first goal for the club – firing the ball into the top corner during first-half stoppage-time – in a 2–0 win over Leeds United at Griffin Park on 27 September. He scored again the following Saturday, converting Alan McCormack's cross for the opening goal in a 3–1 victory over Reading.