Born in Kolkata, Indrani is the youngest child of Dr. Himangshu Jyoti Dutta and Manjushree Dutta. Even as a child while studying in Kamala Girls' High School, Indrani nurtured an ambition to become an actress. Her versatility was reflected in dance and sports. She acquired formal training in dance and music and was a sports topper in her school. Among Indrani's favourite hobbies were listening to music and stamp collecting.
She graduated in Arts from the Sivanath Sastri College, an affiliated college of the prestigious University of Calcutta. Under the able guidance of her Guru Sumitra Mitra, Indrani was conferred Pravakar in Kathak dance by Allahabad University. Her artistic inclinations are reflected in her love for music, interior design and gardening. Her easygoing, down-to-earth, loving nature makes her popular among all age groups. She is also a responsible citizen and environmentalist; with a love for animals, she is an active supporter of the cause of People for Animals.
Indrani's career as an actor is not confined to the big screen. Her performances in telefilms such as Thir Bijuri, Thager Ghar, Swet Mayur, Hatat Bristi and in serials such as Chira Kumar Sabha, Sesh Prasno, Sima Rekha and Louha Kapat is praiseworthy.
In 1997, Indrani acted in one episode of the Hindi TV series Byomkesh Bakshi.
Indrani has a great passion for dance; this passion led her to create her own dance school in Kolkata. Before opening this dance school, she had also had her own dance troupe, named "Srishti". Indrani Dutta Kala Niketan is now a popular and a remarkable dance institution of Kolkata and is well known all over East India. The dance troupe and the dance school have presented many shows in India and overseas.