Rhys Jones came to national attention in the 1980s for his work in the BBC television comedy sketch shows Not the Nine O'Clock News and Alas Smith and Jones. With Smith, he founded television production company Talkback Productions, now part of RTL Group and later in 2005, he started the production company Modern Television.
He went on to develop a career as a television presenter and writer, as well as continuing with acting work. Until 2016, he presented the television bloopers show It'll Be Alright on the Night for ITV, having replaced Denis Norden in 2008.
Griffith Rhys Jones was born in Cardiff, the son of Gwynneth Margaret (née Jones) and Elwyn Rhys Jones, a medical doctor.
The family moved because of his father's occupation to West Sussex when he was 6 months old.