Keyworth was also on the board of directors for Eon Corporation (formally known as TV Answer) from 1990 to 1994. He worked as a liaison between TV Answer and Hewlett-Packard which eventually led to a manufacturing and marketing partnership between the two companies that was designed to speed the development of the first national interactive television system. Keyworth facilitated the agreement between HP and TV Answer to manufacture and market interactive television home units that would activate and control TV Answer’s two-way system in the home.
In early 2005, after news leaks about then-CEO Carly Fiorina's clashes with the board surfaced, Fiorina hired a law firm to find the source. In February 2005, Fiorina left the company and Patricia Dunn, non-executive chairwoman, continued the investigation. As part of a larger scandal, a subcontractor used pretexting to expose Keyworth as the source of an alleged additional leak to CNET, and he was outed at a May 18, 2006 board meeting. At the meeting, Dunn asked Keyworth to resign, he refused asserting that he was not the source of any unauthorized or inappropriate communication with reporters, and another board member (Tom Perkins) resigned over the way Keyworth was being treated. HP revealed the story on September 6, 2006 and said that they were not seeking Keyworth's reelection to the board. Coinciding with Mark V. Hurd's promotion to chairman, Keyworth resigned on September 12. In connection with Keyworth's resignation, HP made the following statement regarding the alleged CNET leak: "At HP's request, Dr. Keyworth often had contacts with the press to explain HP's interests. The board does not believe that Dr. Keyworth's contact with CNET in January 2006 was vetted through appropriate channels, but also recognizes that his discussion with the CNET reporter was undertaken in an attempt to further HP's interests. HP board chairman Patricia Dunn expressed regret for the intrusion into his privacy."