Flavin-containing amine oxidoreductase
Flavin-containing amine oxidoreductases
are a family of various amine oxidases
, including maize polyamine
oxidases (LAO) and various flavin
containing monoamine oxidases
(MAO). The aligned region includes the flavin binding site of these enzymes. In vertebrates, MAO plays an important role in regulating the intracellular levels of amines via their oxidation; these include various neurotransmitters
and trace amines
In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium.
PAOs in plants, bacteria and protozoa oxidise spermidine
to an aminobutyral
and hydrogen peroxide
and are involved in the catabolism
Other members of this family include tryptophan 2-monooxygenase
, putrescine oxidase
-binding proteins, and antibacterial glycoproteins.
AOF1; AOF2; IL4I1; MAOA; MAOB; PAOX; PPOX; SMOX;
This article incorporates text from the public domain Pfam and InterPro IPR002937
This page was last edited on 27 May 2016, at 02:37.
under CC BY-SA license.