Edgar and Ellen live in a 13-story mansion on the edge of Nod's Limbs. Ellen is supposedly the older of the twins by 2 minutes and 13 seconds. They live with a hairy creature who they refer to as Pet — a hairball with an eyeball. Their groundskeeper and caretaker, Heimertz, lives in a small shack just outside the house. Their mansion is located near a now disassembled junkyard, which the twins had lovingly dubbed their "Gadget Graveyard". They take parts from it and create marvelous contraptions for trouble.
Both of the twins wear striped footie pajamas and prank each other all day long—when they're not pranking the goody-goody townspeople of Nod's Limbs. They are clever, fearless, mischievous and creative. So creative, in fact, that their pranks often backfire hilariously.
Books are published by Simon & Schuster in the United States, Canada, and the UK. Internationally books are published by Hachette Children's Book Australia, Pocket Jeunesse (France), Grupo SM in Spain and Editora Rocco in Brazil, among others.
Nod's Limbs is the town where Edgar and Ellen live. It's so sickeningly sweet that it makes your teeth hurt. There is no originality to the people that live there- which is why Edgar and Ellen are such a foil for them. The twins attempt to liven up the place as it's a place so clean and shiny that one just wants to throw mud at it just to mix things up a bit. Living in it is, in the twins' own words, "like living inside a sugar cube".
The TV series was co-produced with Bardel Entertainment in association with YTV and Nicktoons. Nicktoons Network aired Edgar & Ellen two-minute shorts every day. There were thirteen shorts in total. Six holiday specials began airing on Nicktoons Network on Labor Day Weekend 2006. The Back-to-School special, "Accept No Substitutes," was followed by a Halloween special, "Trick or Twins," a winter special, "Cold Medalists," a Valentine's special entitled "Crushed", and an April Fool's special "Nobody's Fools." The most recent one, called "Frog Days of Summer" aired on September 3, 2007.