Charlie Dupont was born in Tournai, Belgium. His acting credits include Hard (2008), Largo Winch II (2011), Let My People Go! (2011), Métal Hurlant Chronicles (2012), Les Petits Meurtres d'Agatha Christie (2013), and Le Dernier Diamant (2014). On November 18, 2014, it was announced that Dupont would host the 5th Magritte Awards.
He has been married to actress Tania Garbarski since 2001. They have two children.