There are traces of human settlement by prehistoric peoples, especially in the Périgord, but the earliest attested inhabitants in the south-west were the Aquitani, who were not proper Celtic people, but more akin to the Iberians (see Gallia Aquitania). Although a number of different languages and dialects were in use in the area during ancient times, it is most likely that the prevailing language of Aquitaine during the late pre-historic to Roman period was an early form of the Basque language. This has been demonstrated by various Aquitanian names and words that were recorded by the Romans, and which are currently easily readable as Basque. Whether this Aquitanian language (Proto-Basque) was a remnant of a Vasconic language group that once extended much farther, or whether it was generally limited to the Aquitaine/Basque region is not known. One reason the language of Aquitaine is important is because Basque is the last surviving non-Indo-European language in western Europe and it has had some effect on the languages around it, including Spanish and, to a lesser extent, French.
The original Aquitania (named after the inhabitants) at the time of Caesar's conquest of Gaul included the area bounded by the Garonne River, the Pyrenees and the Atlantic Ocean. The name may stem from Latin 'aqua', maybe derived from the town "Aquae Augustae", "Aquae Tarbellicae" or just "Aquis" (Dax, Akize in modern Basque) or as a more general geographical feature.
Under Augustus' Roman rule, since 27 BC the province of Aquitania was further stretched to the north to the River Loire, thus including proper Gaul tribes along with old Aquitani south of the Garonne (cf. Novempopulania and Gascony) within the same region.
Accounts of Aquitania during the Early Middle Ages are a blur, lacking precision, but there was much unrest. The Visigoths were called into Gaul as foederati, legalizing their status within the Empire. Eventually they established themselves as the de facto rulers in south-west Gaul as central Roman rule collapsed. Visigoths established their capital in Toulouse, but their tenure on Aquitaine was feeble. In 507, they were expelled south to Hispania after their defeat in the Battle of Vouillé by the Franks, who became the new rulers in the area to the south of the Loire.